dentognostics GmbH is an internationally operating, research and production company based in Jena that has been developing innovations in the field of point-of-care molecular diagnostics for oral health for over 20 years[2]. The company specializes in the early detection and prevention of oral diseases and is considered the world's leading developer of aMMP-8 technology, a predictive biomarker for collagen degradation processes that specifically provides early indications of hidden inflammation in the oral cavity and enables targeted prevention measures[1][2].
The core business of dentognostics is the development, manufacture and marketing of rapid, evidence-based saliva tests – in particular the ORALyzer® system, which enables the measurement of active matrix metalloproteinase-8 (aMMP-8) directly at the treatment chair within a few minutes[1]. This technology makes invisible, subclinical inflammation measurable and supports dentists and medical professionals in recognizing, treating and monitoring the course of diseases such as periodontitis or peri-implantitis at an early stage[1][4]. aMMP-8 diagnostics is scientifically extensively documented (over 400 studies) and is used by leading dental practices, but also by space organizations such as NASA and ESA, as well as in competitive sports[2].
In addition, dentognostics offers laboratory analyses with which the inflammatory status and bacterial causes of periodontitis and peri-implantitis can be identified – a valuable addition for precise diagnostics and therapy planning[4].
The mission of dentognostics is to keep healthy people healthy and to promote early, preventive dentistry through innovation and scientific excellence[2][5]. The company pursues the goal of strengthening oral health as a central pillar of general health and actively promoting the paradigm shift from reactive to proactive dentistry.
The most important values include Innovation, Precision, Sustainability, Practical Relevance and Patient Orientation. dentognostics stands for personalized precision dentistry, i.e. medically and scientifically sound, individually controlled prevention and therapy that keeps the entire organism in view[1]. The technology enables patients to actively manage their oral health and strengthen awareness of the importance of preventive measures[1].
dentognostics pursues a holistic approach to health maintenance that goes beyond the mere treatment of symptoms. By avoiding inflammation at an early stage, not only are invasive and costly therapies reduced, but the quality of life of patients is also maintained in the long term. aMMP-8 diagnostics also serves as a prophylaxis for systemic diseases, as oral inflammation can be associated with numerous general diseases[1].
The company continuously invests in Research and Development to establish innovative, resource-saving and efficient diagnostic procedures. The close cooperation with international research partners, medical institutions and organizations of space medicine underlines the endeavor to develop interdisciplinary solutions for global health challenges[2].
With more than 40 patents in the field of molecular diagnostics, dentognostics is a Global Player and is met with great resonance among international dental practices, clinics, medical laboratories and scientific institutions[2]. The technology is also used in top-class sport and in special environments such as space simulations, which proves the versatility and reliability of aMMP-8 diagnostics[2].
The team consists of highly qualified scientists, engineers and physicians who work together on the vision of enabling healthy aging with natural teeth and implants[5]. Regular training courses and close cooperation with practitioners on site ensure that the latest scientific findings are directly incorporated into dental care.
dentognostics GmbH is an innovative provider of point-of-care diagnostics for oral and dental implant health. The patented aMMP-8 technology enables the early detection and prevention of oral inflammation, contributes to maintaining the health of the entire organism and sets standards for modern, scientifically sound prophylaxis and therapy in dentistry[1][2][4]. Through practical, precise and scientifically validated solutions, dentognostics makes a decisive contribution to sustainable, patient-oriented healthcare.
