PhD Candidate (f/m/x) in Endothelial Mechanobiology and Cellular Signaling

At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives.

The Georgiadi Lab (Group of Endocrine Pharmacology) at the Institute for Diabetes and Cancer (IDC) studies how vascular and metabolic signaling regulate adipose tissue function in obesity, aging, and cardiometabolic disease. Our work combines endothelial biology, mechanobiology, GPCR signaling, multi-omics, and metabolic phenotyping to understand how adipose tissue adapts to physiological and pathological stress.

The project is embedded within the DFG-funded Collaborative Research Centre TRR333, an interdisciplinary network focused on brown adipose tissue biology and metabolic health.

Your tasks

Develop and optimize in vitro models to investigate endothelial biology under defined mechanical and molecular conditions
Establish advanced experimental systems, including co-culture and microfluidic approaches, to study cellular responses under flow
Design and perform functional assays to investigate GPCR signaling and mechanobiological processes
Collaborate closely with computational researchers to validate candidate mechanisms and generate integrated biological insights
Present and publish research findings and contribute to collaborative in vivo studies

Your profile

Master's degree in Biochemistry, Molecular Biology, Biomedical Sciences, Bioengineering, or a related field
Hands-on experience with cell culture and molecular biology techniques
Strong interest in mechanobiology, vascular biology, or receptor signaling
Motivation to work in an interdisciplinary and collaborative research environment
Excellent written and spoken English skills

Desirable qualifications

Experience or strong interest in bioengineering, microfluidics, or advanced in vitro model systems
Experience with functional assay development or GPCR signaling
Willingness to contribute to in vivo experiments

This position provides the opportunity for you to build specialist knowledge whilst developing key professional experience, both of which will help you to make strides in your scientific career.

Remuneration and social security benefits are based on the German Collective Wage Agreement for Public-Sector Employees at Federal Level (EG 13 50%TV EntgO Bund). In addition, there is also the possibility of receiving an allowance if the applicable conditions are met. The position has an (initial) fixed term of three years but may be extended under certain circumstances.

Managing Director Mike Frieser:

„We believe that diversity is the key to groundbreaking research and innovative solutions. Our flexible working models and remote options create a supportive environment for balancing work and family life. For us, contributing to a healthier society in such an inspiring workplace is truly meaningful.“

Get to know us

Benefits

Career counseling

Career Center for PhD candidates

Family Support

On-site kindergarten, holiday care, care for the elderly

Health Promotion

Sports, company doctor, mental health initiatives

International Staff Service

Support with the relocation and integration process in Germany

Scientific Resources

State-of-the-art infrastructure and Core Facilities

Scientific Training

Helmholtz Munich Graduate School

Scientific Training: Helmholtz Munich Graduate School
Career counseling: Career Center for PhD candidates
Scientific Resources: State-of-the-art infrastruture and Core Facilities
Health Promotion: Sports, company doctor, mental health initiatives
International Staff Service: Support with the relocation and integration process in Germany

Interested in applying?

If you have any questions, feel free to contact Dr. Anja Marschner, anja.marschner@helmholtz-munich.de, who will be happy to help.

Our recruiting is decentralized - your application will be reviewed directly by the specialist department in which you could work in the future.

More information about our application process

Please send your application only via our online application tool and with the following documents:

CV
Cover letter
Degrees/Diplomas/Certificates
References from recent employers
Contact details for at least two referees
List of publications

If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree by the time you start work at the latest.Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.

Learn more about diversity at Helmholtz Munich

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PhD Candidate*in in Endothelial Mechanobiology and Cellular Signaling

PhD Candidate*in in Endothelial Mechanobiology and Cellular Signaling