Scientific Programmer—Computational Protein Design and Engineering

Your qualifications

• PhD in Bioinformatics, Structural Biology, Biophysics, Biochemistry, or related fields
• Experience in computational protein design and/or engineering
• Solid knowledge of scientific software engineering
• Experience with some (ideally all) of the following software packages: RFdiffusion, ProteinMPNN, Rosetta, AlphaFold
• Experience in conducting (ideally managing), interdisciplinary research projects and communication
• Know-how in the administration of computational infrastructure for the purpose of computational protein design/engineering

Your responsibilities

This scientific programmer will be responsible for the development and implementation of computational workflows for protein design and engineering. They will oversee and support the execution of these projects, and administrate the available hardware. Key responsibilities are:

• Perform lab visits to consult, discuss and identify specific needs and opportunities for the application of protein design/engineering
• Work in close collaboration with Protein Design Accelerator Technology Hub, which is also part of BioSysteM, and located in close vicinity at the same campus
• Provide introductory courses for the computational workflows in this domain
• Work closely with scientists to develop advanced computational workflows, with the prospect of taking a leading role in some of these projects
• Advise and support researchers in their protein design/engineering tasks
• Administration of hardware and software to be used in the protein design/engineering domain: The hired scientific programmer will have hardware at their disposal, which should be usable for members of BioSysteM
• Research data management: Develop and monitor data harmonization within the cluster with respect to protein design/engineering (in collaboration with the Data Stewards of BioSysteM)
• Connect researchers working on similar problems and involve external experts (via the AI Advisory Board of BioSysteM, and the Munich Data Science Institute, MDSI)

Our offer

We offer a full-time position as academic staff with the opportunity to work within a team of experts (domain specialists) in the AI Core Unit. The AI Core Unit is embedded in an excellent research environment and comes with outstanding, independently managed equipment and resources. The position will be limited to the funding period of BioSysteM. Payment will be based on the Collective Agreement for the Civil Service of the Länder (TV-L).

TUM strives to raise the proportion of women in its workforce and explicitly encourages applications from qualified women. The position is suitable for disabled persons. Disabled applicants will be given preference in case of generally equivalent suitability, aptitude and professional performance.

Your application

• If you are interested in working in our team, please send your application together with a strong CV and supporting documentation in one single pdf to into@biosystem.design (by 6 Sept the latest)
• Do not hesitate to contact patrick.quoika@tum.de in case of any questions.
• Find out more about us at www.biosystem.design

The position is suitable for disabled persons. Disabled applicants will be given preference in case of generally equivalent suitability, aptitude and professional performance.