Perform bioinformatic analyses on brain insulin resistance and the epigenetic regulation of type 2 diabetes subtypes., Develop analysis pipelines to extract deeper insights from existing epigenetic and phenotypic datasets., Analyze blood DNA methylation from a large cohort., Apply machine and deep learning methods to build an epigenetic risk score., Optimize a data-integration pipeline combining epigenetic and proteomic data into a composite score., Analyze DNA methylation in muscle biopsies., Integrate methylome and transcriptome data to predict the relationship between DNA methylation and alternative splicing., Use established clustering methods in the group (PAM and WGCNA)., Integrate clinical and epigenetic data for correlation analyses., Use machine and deep learning to derive an epigenetic risk score., Apply PAM and WGCNA for data-driven patient stratification.