European Molecular Biology Laboratory (EMBL)embl.org
Laboratory Officer
- Standort
- Heidelberg
- Remote
- Vor Ort
- Anstellungsart
- Vollzeit
- Erfahrung
- Mid-Level
- Bereich
- Forschung & Wissenschaft
- Gehalt
- Ab 49.775 EUR/Jahr
- Bewerbungsfrist
- 30.09.2026
vor 4 Tagen
The Dorrity group at EMBL Heidelberg is seeking a motivated and skilled molecular biologist to join as a Laboratory Officer. Our group uses cutting-edge single-cell genomic techniques to study how cells regulate gene expression over time, with the goal of understanding how individual cells make decisions, respond to environmental signals, and establish stable identities. The position is primarily focused on wet lab work and centers on two complementary areas: maintaining and engineering mammalian cell culture systems, and developing novel low-input sequencing protocols adapted from state-of-the-art single-cell genomics approaches. An interest in learning basic programming or bioinformatics is a plus, but not required. If you are motivated to push the boundaries of what genomics can measure and want to do it in a collaborative, fast-moving environment, we want to hear from you.
Your role
Scientific Research:
- Establishment, maintenance, and engineering of mammalian cell culture systems, including generation of stable cell lines using plasmid transfection and genomic integration approaches
- Troubleshooting and adapting single-cell RNA sequencing protocols for low-input samples, including systematic optimisation of lysis, reverse transcription, and library preparation conditions
- Preparation and quality control of next-generation sequencing libraries
- Performing single-cell combinatorial indexing experiments (e.g. sci-RNA-seq). No prior experience required
- Cloning and engineering constructs in microbial systems (E. coli) for downstream mammalian applications
- Design and execution of mammalian cell perturbation experiments in collaboration with other group members
- Using CRISPR/Cas systems for genomic engineering of mammalian cell lines
Lab management, training and supervision:
- Onboarding and training of new group members or visitors in technologies and protocols used in the laboratory
- Testing new tools, reagents, and updates to experimental protocols
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